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Thomas J Herzog Selected Research

Drug Therapy (Chemotherapy)

1/2024Molecular profiling of gestational trophoblastic neoplasia: Identifying therapeutic targets.
8/2023Acute pulmonary complications in the setting of high risk gestational trophoblastic neoplasia and induction of chemotherapy.
7/2023ARTISTRY-7: phase III trial of nemvaleukin alfa plus pembrolizumab vs chemotherapy for platinum-resistant ovarian cancer.
1/2023Dostarlimab for Primary Advanced or Recurrent Endometrial Cancer.
1/2023Overcoming the challenges of drug development in platinum-resistant ovarian cancer.
1/2023Randomized phase II trial of farletuzumab plus chemotherapy versus placebo plus chemotherapy in low CA-125 platinum-sensitive ovarian cancer.
1/2022What proportion of patients with stage 3 ovarian cancer are potentially cured following intraperitoneal chemotherapy? Analysis of the long term (≥10 years) survivors in NRG/GOG randomized clinical trials of intraperitoneal and intravenous chemotherapy in stage III ovarian cancer.
12/2021ATHENA (GOG-3020/ENGOT-ov45): a randomized, phase III trial to evaluate rucaparib as monotherapy (ATHENA-MONO) and rucaparib in combination with nivolumab (ATHENA-COMBO) as maintenance treatment following frontline platinum-based chemotherapy in ovarian cancer.
12/2020Gemogenovatucel-T (Vigil) immunotherapy as maintenance in frontline stage III/IV ovarian cancer (VITAL): a randomised, double-blind, placebo-controlled, phase 2b trial.
7/2020Early diagnosis and treatment challenges of endodermal sinus tumors: A case report.
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Thomas J Herzog Research Topics

Disease

85Ovarian Neoplasms (Ovarian Cancer)
11/2023 - 01/2002
69Neoplasms (Cancer)
04/2024 - 03/2002
23Uterine Cervical Neoplasms (Cancer of the Cervix)
01/2022 - 06/2003
21Endometrial Neoplasms (Endometrial Cancer)
11/2023 - 06/2002
16Carcinoma (Carcinomatosis)
11/2022 - 01/2002
13Ovarian Epithelial Carcinoma
01/2023 - 01/2004
6Disease Progression
10/2023 - 09/2003
6Neoplasm Metastasis (Metastasis)
08/2023 - 03/2004
6Neutropenia
02/2017 - 01/2002
6Ascites
06/2015 - 01/2002
5Fatigue
01/2023 - 10/2014
5Hypertension (High Blood Pressure)
01/2017 - 11/2004
4Sarcoma (Soft Tissue Sarcoma)
01/2021 - 12/2004
4Thrombocytopenia (Thrombopenia)
10/2014 - 01/2002
4Lymphatic Metastasis
12/2004 - 06/2003
3Nausea
01/2023 - 11/2014
3Febrile Neutropenia
01/2017 - 01/2004
3Infections
01/2017 - 11/2004
3Hemorrhage
07/2014 - 08/2013
3Wounds and Injuries (Trauma)
10/2013 - 06/2010
3Venous Thromboembolism
11/2011 - 06/2010
2Gestational Trophoblastic Disease (Trophoblastic Neoplasms, Gestational)
01/2024 - 08/2023
2Fallopian Tube Neoplasms
12/2021 - 01/2017
2Fever (Fevers)
01/2021 - 11/2014
2Endodermal Sinus Tumor (Endodermal Sinus Tumors)
07/2020 - 11/2004
2Uterine Neoplasms (Uterine Cancer)
01/2020 - 07/2013
2COVID-19
01/2020 - 01/2020
2Leiomyosarcoma
12/2018 - 11/2008
2Vomiting
02/2017 - 11/2014
2Proteinuria
01/2017 - 07/2014
2Endometriosis
01/2016 - 08/2013
2Abdominal Pain (Pain, Abdominal)
11/2014 - 07/2014
2Female Genital Diseases
05/2014 - 02/2013
2Pelvic Organ Prolapse
08/2013 - 11/2012
2Vulvar Neoplasms (Vulvar Cancer)
07/2013 - 09/2008
2Adenocarcinoma
01/2012 - 12/2007
2Clear Cell Adenocarcinoma
01/2009 - 12/2004
2Hemolytic-Uremic Syndrome
04/2005 - 11/2004
2Anemia
11/2004 - 01/2002
1Lung Diseases (Lung Disease)
08/2023
1Lung Injury
08/2023
1Alopecia (Baldness)
01/2023
1Genomic Instability
01/2023

Drug/Important Bio-Agent (IBA)

32PlatinumIBA
10/2023 - 01/2002
17Paclitaxel (Taxol)FDA LinkGeneric
10/2023 - 01/2002
17liposomal doxorubicin (Doxil)FDA Link
01/2023 - 01/2002
13Biomarkers (Surrogate Marker)IBA
01/2023 - 06/2010
11Carboplatin (JM8)FDA LinkGeneric
01/2023 - 01/2004
11Topotecan (Hycamtin)FDA LinkGeneric
03/2011 - 01/2002
101-dodecylpyridoxal (PLD)IBA
11/2021 - 04/2005
8Proteins (Proteins, Gene)FDA Link
04/2024 - 01/2004
7Bevacizumab (Avastin)FDA Link
01/2023 - 11/2010
7TrabectedinIBA
01/2021 - 07/2010
6taxaneIBA
01/2017 - 08/2006
5FANG vaccineIBA
02/2023 - 12/2020
5Poly(ADP-ribose) Polymerase InhibitorsIBA
01/2023 - 01/2019
4DNA (Deoxyribonucleic Acid)IBA
09/2023 - 06/2002
4Hormones (Hormone)IBA
01/2020 - 06/2010
4Cisplatin (Platino)FDA LinkGeneric
01/2019 - 07/2004
4GemcitabineFDA Link
03/2010 - 01/2004
4VaccinesIBA
05/2008 - 09/2003
4Deoxyglucose (2 Deoxy D glucose)IBA
12/2005 - 06/2003
3AntigensIBA
01/2023 - 07/2016
3Monoclonal AntibodiesIBA
01/2023 - 01/2016
3Docetaxel (Taxotere)FDA Link
03/2014 - 08/2003
3Topoisomerase I InhibitorsIBA
05/2008 - 01/2002
2Immune Checkpoint InhibitorsIBA
10/2023 - 12/2021
2farletuzumabIBA
01/2023 - 01/2016
2Immunoconjugates (Immunoconjugate)IBA
01/2023 - 01/2023
2EpitopesIBA
01/2022 - 12/2021
2CytokinesIBA
01/2022 - 11/2014
2Folic Acid (Vitamin M)FDA LinkGeneric
11/2016 - 01/2016
2pazopanibFDA Link
03/2016 - 10/2014
2Progestins (Progestagens)IBA
09/2015 - 01/2004
2Phosphotransferases (Kinase)IBA
07/2013 - 02/2013
2Etoposide (VP 16)FDA LinkGeneric
11/2004 - 11/2004
1niraparibIBA
11/2023
1ParaffinIBA
09/2023
1Formaldehyde (Formol)FDA Link
09/2023
1pembrolizumabIBA
07/2023
1anetumab ravtansineIBA
01/2023
1Folic Acid AntagonistsIBA
01/2023
1MesothelinIBA
01/2023

Therapy/Procedure

59Therapeutics
01/2024 - 01/2002
36Drug Therapy (Chemotherapy)
01/2024 - 01/2002
28Hysterectomy
10/2021 - 08/2004
9Immunotherapy
10/2023 - 01/2019
9Radiotherapy
08/2014 - 09/2003
8Lymph Node Excision (Lymph Node Dissection)
01/2013 - 04/2002
4Ovariectomy (Oophorectomy)
10/2021 - 04/2002
4Laparotomy
11/2004 - 03/2004
3Cytoreduction Surgical Procedures
12/2021 - 12/2011
3Adjuvant Chemotherapy
01/2019 - 10/2018
3Brachytherapy
08/2014 - 12/2011
3Neoadjuvant Therapy
04/2014 - 09/2008
3Adjuvant Radiotherapy
04/2009 - 10/2003
2Precision Medicine
01/2022 - 06/2012
2Length of Stay
06/2010 - 09/2003
2Aftercare (After-Treatment)
01/2007 - 11/2004
2Catheters
05/2006 - 01/2002